haloperidol

Ligand id: 86

Name: haloperidol

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: haloperidol

Structure and Physico-chemical Properties

2D Structure
Click here for structure editor
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 40.54
Molecular weight 375.14
XLogP 4.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1967))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
IUPAC Name
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
International Nonproprietary Names
INN number INN
918 haloperidol
Synonyms
Haldol® | MCN-JR-1625 | R-1625 | Serenace®
Comments
Haloperidol is a typical antipsychotic drug.
Database Links
BindingDB Ligand 21398
BitterDB Ligand 66
CAS Registry No. 52-86-8
ChEBI CHEBI:5613
ChEMBL Ligand CHEMBL54
DrugBank Ligand DB00502
GtoPdb PubChem SID 135650345
PubChem CID 3559
RCSB PDB Ligand GMJ
Search Google for chemical match using the InChIKey LNEPOXFFQSENCJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LNEPOXFFQSENCJ
Search PubMed clinical trials haloperidol
Search PubMed titles haloperidol
Search PubMed titles/abstracts haloperidol
Search UniChem for chemical match using the InChIKey LNEPOXFFQSENCJ-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LNEPOXFFQSENCJ
Wikipedia Haloperidol