SB 216641 [Ligand Id: 28] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL20963 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| 5-HT1B receptor/Serotonin 1b (5-HT1b) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1898] [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
| GtoPdb | - | - | 9 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
| ChEMBL | Binding affinity for human 5-hydroxytryptamine 1B receptor | B | 9 | pKi | 1 | nM | Ki | J Med Chem (1998) 41: 1218-1235 [PMID:9548813] |
| 5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
| ChEMBL | Binding affinity for human 5-hydroxytryptamine 1D receptor | B | 7.5 | pKi | 31.62 | nM | Ki | J Med Chem (1998) 41: 1218-1235 [PMID:9548813] |
| GtoPdb | - | - | 7.6 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
| 5-HT2A receptor/Serotonin 2a (5-HT2a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL224] [GtoPdb: 6] [UniProtKB: P28223] | ||||||||
| ChEMBL | Binding affinity for human 5-hydroxytryptamine 2A receptor | B | 7.3 | pKi | 50.12 | nM | Ki | J Med Chem (1998) 41: 1218-1235 [PMID:9548813] |
| GtoPdb | - | - | 7.3 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
| 5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
| GtoPdb | - | - | 6.3 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
| 5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595] | ||||||||
| GtoPdb | - | - | 5.8 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
| 5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335] | ||||||||
| GtoPdb | - | - | 6.8 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (1997) 356: 312-20 [PMID:9303567] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
