[3H]pentazocine [Ligand Id: 6683] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL2311194 ((+)-[3H]-Pentazocine, [3H]-(+)-Pentazocine)
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Sigma-1 receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4153] [UniProtKB: Q60492]
ChEMBL Binding affinity to guinea pig brain sigma1 receptor B 8.54 pKd 2.9 nM Kd J. Med. Chem. (2012) 55: 5350-5360 [PMID:22515405]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]