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brentuximab vedotin   Click here for help

GtoPdb Ligand ID: 6772

Synonyms: Adcetris® | anti-CD30 ADC SGN-35 | SGN 35
Approved drug Immunopharmacology Ligand
brentuximab vedotin is an approved drug (FDA (2011), EMA (2012))
Compound class: Antibody
Comment: Antibody-drug conjugate (ADC) that combines an anti-CD30 antibody and the drug monomethyl auristatin E (MMAE). The PubChem ID for the MMAE component compound is CID 11542188. The invention of this ADC is claimed in patent US7090843 [4] and the original article describing the parent antibody (C10 or AC10) is [1].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Classification Click here for help
Compound class Antibody
Approved drug? Yes. US FDA (2011)  |  EU EMA (2012)
International Nonproprietary Names Click here for help
INN number INN
9144 brentuximab vedotin
Synonyms Click here for help
Adcetris® | anti-CD30 ADC SGN-35 | SGN 35
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 324
Other databases
GtoPdb PubChem SID 178103378
PubChem SID 178103378
Search PubMed clinical trials brentuximab vedotin
Search PubMed titles brentuximab vedotin
Search PubMed titles/abstracts brentuximab vedotin
Wikipedia Brentuximab_vedotin