ChEMBL ligand: CHEMBL146746
Glutamyl aminopeptidase/Aminopeptidase A in Human [ChEMBL: CHEMBL3439] [GtoPdb: 1568] [UniProtKB: Q07075] Glutamyl aminopeptidase in Mouse [GtoPdb: 1568] [UniProtKB: P16406] There should be some charts here, you may need to enable JavaScript!
Aminopeptidase N in Pig [ChEMBL: CHEMBL2590] [UniProtKB: P15145] There should be some charts here, you may need to enable JavaScript!
Angiotensin-converting enzyme in Rat [ChEMBL: CHEMBL2625] [GtoPdb: 1613] [UniProtKB: P47820] There should be some charts here, you may need to enable JavaScript!
Neprilysin in Rabbit [ChEMBL: CHEMBL3768] [UniProtKB: P08049] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Glutamyl aminopeptidase/Aminopeptidase A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3439] [GtoPdb: 1568] [UniProtKB: Q07075]
ChEMBL	Binding affinity against recombinant Aminopeptidase A	B	9.06	pKi	0.87	nM	Ki	J Med Chem (1999) 42: 5197-5211 [PMID:10602705]
Glutamyl aminopeptidase in Mouse [GtoPdb: 1568] [UniProtKB: P16406]
GtoPdb	-	-	9.06	pKi	0.87	nM	Ki	J Med Chem (1999) 42: 5197-211 [PMID:10602705]
Aminopeptidase N in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2590] [UniProtKB: P15145]
ChEMBL	Binding affinity against aminopeptidase N from pig kidney	B	4.79	pKi	16400	nM	Ki	J Med Chem (1999) 42: 5197-5211 [PMID:10602705]
Angiotensin-converting enzyme in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2625] [GtoPdb: 1613] [UniProtKB: P47820]
ChEMBL	Binding affinity against Angiotensin I converting enzyme from rat testis	B	6.59	pKi	259	nM	Ki	J Med Chem (1999) 42: 5197-5211 [PMID:10602705]
Neprilysin in Rabbit (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3768] [UniProtKB: P08049]
ChEMBL	Binding affinity against NEP from rabbit kidney(neutral endopeptidase)	B	6.66	pKi	219	nM	Ki	J Med Chem (1999) 42: 5197-5211 [PMID:10602705]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]