Synonyms: compound 65 [PMID 24666157]
Compound class:
Synthetic organic
Comment: ML321 is a dopamine D2 receptor selective antagonist [2] which is a suitable tool compound for the dissection of D2 receptor modulation in proof-of-concept animal studies and provides medicinal chemists a lead structure for the development of novel D2 receptor selective drugs.
![]() Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Classification ![]() |
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Compound class | Synthetic organic |
IUPAC Name ![]() |
(11S)-5-methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide |
Synonyms ![]() |
compound 65 [PMID 24666157] |
Database Links ![]() |
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Specialist databases | |
GPCRdb Ligand | ML321 |
Other databases | |
BindingDB Ligand | 50003074 |
ChEMBL Ligand | CHEMBL3234544 |
GtoPdb PubChem SID | 252166580 |
PubChem CID | 57377246 |
Search Google for chemical match using the InChIKey | YXLLQNMKIDBOGH-NDEPHWFRSA-N |
Search Google for chemicals with the same backbone | YXLLQNMKIDBOGH |
UniChem Compound Search for chemical match using the InChIKey | YXLLQNMKIDBOGH-NDEPHWFRSA-N |
UniChem Connectivity Search for chemical match using the InChIKey | YXLLQNMKIDBOGH-NDEPHWFRSA-N |