NS3763 [Ligand Id: 4274] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL156717 (NS-3763)
  • GluK1/Glutamate receptor ionotropic kainate 1 in Human [ChEMBL: CHEMBL1918] [GtoPdb: 450] [UniProtKB: P39086]
  • This target only has 0 pki data point
  • 0
1 CHEMBL156717_lig_chart_1 Glutamate receptor ionotropic kainate 1 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GluK1/Glutamate receptor ionotropic kainate 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1918] [GtoPdb: 450] [UniProtKB: P39086]
ChEMBL In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells. B 5.8 pIC50 1600 nM IC50 J. Med. Chem. (2003) 46: 5834-5843 [PMID:14667236]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]