pegaptanib   Click here for help

GtoPdb Ligand ID: 6836

Synonyms: EYEOO1 | Macugen® | NX183 | pegaptanib sodium
Approved drug
pegaptanib is an approved drug (FDA (2004), EMA (2006))
Compound class: Synthetic organic
Comment: Pegaptanib is a RNA oligonucleotide aptamer that cts as a vascular endothelial growth factor A antagonist, anti-angiogenic agent.
It is a 28-mer RNA aptamer that is covalently linked to two branched 20-kD polyethylene glycol (PEG) chains.
2D Structure
Click here for help

2D Structure

An image of the ligand's 2D structure. For small molecules with SMILES these are drawn using the NCI/CADD Chemical Identifier Resolver. Click on the image to access the chemical structure search tool with the ligand pre-loaded in the structure editor. For other types of ligands, e.g. longer nucleotides and peptides, a manually drawn representation of the molecule may be provided.

✖
Click here for structure editor
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (2004), EMA (2006))
International Nonproprietary Names Click here for help
INN number INN
8215 pegaptanib
Synonyms Click here for help
EYEOO1 | Macugen® | NX183 | pegaptanib sodium
Database Links Click here for help
Specialist databases
Reactome Drug Reactome logo R-ALL-9679463
Reactome Reaction Reactome logo R-HSA-9679477
Other databases
CAS Registry No. 222716-86-1
DrugBank Ligand DB04895
GtoPdb PubChem SID 178103442
PubChem CID 56603655
Search PubMed clinical trials pegaptanib
Search PubMed titles pegaptanib
Search PubMed titles/abstracts pegaptanib
Wikipedia Pegaptanib