triamcinolone acetonide [Ligand Id: 2867] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1504 (Adcortyl, Adcortyl in orabase, Allernaze, Aristocort, Aristocort a, Aristogel, Audicort, Aureocort, Azmacort, Flutex, FX-006, FX006, Gppe ear dps cap, Gppe ear oint, Kenacort, Kenacourt, Kenalog, Kenalog-10, Kenalog-40, Kenalog-80, Kenalog-h, Kenalog in orabase, Nasacort, Nasacort allergy 24 hour, Nasacort aq, Nasacort hfa, NSC-21916, Nystadermal, Oracort, Oralone, Pevaryl t.c., Remiderm, Remotic, Silderm, Triacet, Triacort, Tri-adcortyl, Triamcinolone acetonide, Triamcinolone Acetonide, Triamcinolone acetonide in absorbase, Triatex, Triderm, Triesence, Tri-Nasal, Trivaris, Trymex, Vetalog, Xipere, Zilretta) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Glucocorticoid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2034] [GtoPdb: 625] [UniProtKB: P04150] | ||||||||
| ChEMBL | DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) | B | 8.7 | pKi | 2.01 | nM | Ki | DrugMatrix in vitro pharmacology data |
| GtoPdb | - | - | 8.2 | pIC50 | - | - | - |
Endocrinology (1981) 108: 1414-9 [PMID:7472274]; Brain Res (1995) 685: 105-16 [PMID:7583234] |
| ChEMBL | DRUGMATRIX: Glucocorticoid radioligand binding (ligand: [3H] Dexamethasone) | B | 8.36 | pIC50 | 4.41 | nM | IC50 | DrugMatrix in vitro pharmacology data |
| Progesterone receptor in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1909044] [UniProtKB: Q690N0] | ||||||||
| ChEMBL | DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) | B | 7.64 | pKi | 23 | nM | Ki | DrugMatrix in vitro pharmacology data |
| ChEMBL | DRUGMATRIX: Progesterone radioligand binding (ligand: [3H] R-5020) | B | 6.75 | pIC50 | 179 | nM | IC50 | DrugMatrix in vitro pharmacology data |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
