BIA 10-2474 [Ligand Id: 9001] activity data from GtoPdb

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  • Fatty acid amide hydrolase in Human [GtoPdb: 1400] [UniProtKB: O00519]
  • Fatty acid amide hydrolase in Rat [GtoPdb: 1400] [UniProtKB: P97612]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 Fatty acid amide hydrolase HumanRat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Fatty acid amide hydrolase in Human [GtoPdb: 1400] [UniProtKB: O00519]
GtoPdb Inhibition of human FAAH expressed in HEK293T cells. - 7.3 pIC50 50 nM IC50 Science (2017) 356: 1084-1087 [PMID:28596366]
Fatty acid amide hydrolase in Rat [GtoPdb: 1400] [UniProtKB: P97612]
GtoPdb This value is an extrapolated estimate from % inhibition data provided in Table 1 of the referenced patent. - 6.7 pIC50 ~200 nM IC50 WO2010074588 A2. Pharmaceutical compounds. (2010)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.