RS 39066 [Ligand Id: 8567] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL288896 (RS-39066) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| MMP1/Matrix metalloproteinase-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL332] [GtoPdb: 1628] [UniProtKB: P03956] | ||||||||
| ChEMBL | Inhibition of human fibroblast collagenase, matrix metalloprotease-1 | B | 8.16 | pIC50 | 6.9 | nM | IC50 | Bioorg Med Chem Lett (1996) 6: 1601-1606 |
| MMP3/Matrix metalloproteinase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL283] [GtoPdb: 1630] [UniProtKB: P08254] | ||||||||
| ChEMBL | Inhibition of human fibroblast stromelysin, matrix metalloprotease-3 | B | 9.1 | pIC50 | 0.8 | nM | IC50 | Bioorg Med Chem Lett (1996) 6: 1601-1606 |
| MMP7/Matrix metalloproteinase 7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4073] [GtoPdb: 1631] [UniProtKB: P09237] | ||||||||
| ChEMBL | Inhibition of matrilysin, matrix metalloprotease-7 | B | 9.64 | pIC50 | 0.23 | nM | IC50 | Bioorg Med Chem Lett (1996) 6: 1601-1606 |
| GtoPdb | - | - | 9.64 | pIC50 | 0.23 | nM | IC50 | Bioorg Med Chem Lett (1996) 6: 1601-1606 |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
