ceftezole   Click here for help

GtoPdb Ligand ID: 12259

Synonyms: ceftezol | FR10123
Compound class: Synthetic organic
Comment: Ceftezole is a first generation cephalosporin belonging to the β-lactam class of antibacterial compounds [1].
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 11
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 234.93
Molecular weight 440.01
XLogP 0.43
No. Lipinski's rules broken 1
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Canonical SMILES O=C(N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)O)CSc1nncs1)Cn1cnnn1
Isomeric SMILES C1C(=C(N2[C@H](S1)[C@@H](C2=O)NC(=O)Cn1cnnn1)C(=O)O)CSc1nncs1
InChI InChI=1S/C13H12N8O4S3/c22-7(1-20-4-14-18-19-20)16-8-10(23)21-9(12(24)25)6(2-26-11(8)21)3-27-13-17-15-5-28-13/h4-5,8,11H,1-3H2,(H,16,22)(H,24,25)/t8-,11-/m1/s1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
(6R,7R)-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-3-(1,3,4-thiadiazol-2-ylsulfanylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
International Nonproprietary Names Click here for help
INN number INN
3914 ceftezole
Synonyms Click here for help
ceftezol | FR10123
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Ceftezole
Other databases
CAS Registry No. 26973-24-0 (source: Scifinder)
ChEBI CHEBI:135716
ChEMBL Ligand CHEMBL1697829
DrugBank Ligand DB13821
DrugCentral Ligand 561
GtoPdb PubChem SID 473153847
PubChem CID 65755
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UniChem Compound Search for chemical match using the InChIKey DZMVCVMFETWNIU-LDYMZIIASA-N
UniChem Connectivity Search for chemical match using the InChIKey DZMVCVMFETWNIU-LDYMZIIASA-N