clobetasone   Click here for help

GtoPdb Ligand ID: 9088

Synonyms: Eumovate®
Approved drug Immunopharmacology Ligand
clobetasone is an approved drug (UK (1999))
Compound class: Synthetic organic
Comment: Clobetasone is a corticosteroid used in dermatology.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 71.44
Molecular weight 408.15
XLogP 1.38
No. Lipinski's rules broken 0
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Canonical SMILES ClCC(=O)C1(O)C(C)CC2C1(C)CC(=O)C1(C2CCC2=CC(=O)C=CC12C)F
Isomeric SMILES ClCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)CC(=O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F
InChI InChI=1S/C22H26ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-16,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,19-,20-,21-,22-/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (UK (1999))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
3155 clobetasone
Synonyms Click here for help
Database Links Click here for help
GtoPdb PubChem SID 315661173
PubChem CID 71387
Search Google for chemical match using the InChIKey XXIFVOHLGBURIG-OZCCCYNHSA-N
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UniChem Compound Search for chemical match using the InChIKey XXIFVOHLGBURIG-OZCCCYNHSA-N
UniChem Connectivity Search for chemical match using the InChIKey XXIFVOHLGBURIG-OZCCCYNHSA-N
Wikipedia Clobetasone