compound 16 [PMID: 17585909] [Ligand Id: 12977] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1231507 (Palmitoylaminocarnitine) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| carnitine palmitoyltransferase 1A/Carnitine O-palmitoyltransferase 1, liver isoform in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1293194] [GtoPdb: 3249] [UniProtKB: P50416] | ||||||||
| ChEMBL | Inhibition of human CPT1A | B | 5.57 | pIC50 | 2670 | nM | IC50 | J Med Chem (2011) 54: 3109-3152 [PMID:21504156] |
| carnitine palmitoyltransferase 1B/Carnitine O-palmitoyltransferase 1, muscle isoform in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2216739] [GtoPdb: 3250] [UniProtKB: Q92523] | ||||||||
| ChEMBL | Inhibition of human CPT1B | B | 4.66 | pIC50 | 21700 | nM | IC50 | J Med Chem (2011) 54: 3109-3152 [PMID:21504156] |
| carnitine palmitoyltransferase 2/Carnitine palmitoyltransferase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3238] [GtoPdb: 3252] [UniProtKB: P23786] | ||||||||
| ChEMBL | Inhibition of human CPT2 | B | 6.85 | pIC50 | 140 | nM | IC50 | J Med Chem (2011) 54: 3109-3152 [PMID:21504156] |
| carnitine palmitoyltransferase 2 in Rat [GtoPdb: 3252] [UniProtKB: P18886] | ||||||||
| GtoPdb | - | - | 6.68 | pIC50 | 210 | nM | IC50 | FEBS Lett (2007) 581: 3247-52 [PMID:17585909] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
