dBET6

Ligand id: 10534

Name: dBET6

Structure and Physico-chemical Properties

2D Structure
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Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 3
Rotatable bonds 18
Topological polar surface area 221.77
Molecular weight 840.28
XLogP 6.29
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Ligand families/groups PROTACs and molecular glues
Comments
dBET6 is a BRD4-targeting, cereblon (CRBN)-engaging degrader (or PROTAC; proteolysis targeting chimera) [1].
Database Links
CAS Registry No. 1950634-92-0 (source: PubChem)
GtoPdb PubChem SID 387065616
PubChem CID 121427831
Search Google for chemical match using the InChIKey JGQPZPLJOBHHBK-UFXYQILXSA-N
Search Google for chemicals with the same backbone JGQPZPLJOBHHBK
Search UniChem for chemical match using the InChIKey JGQPZPLJOBHHBK-UFXYQILXSA-N
Search UniChem for chemicals with the same backbone JGQPZPLJOBHHBK