faricimab   Click here for help

GtoPdb Ligand ID: 11420

Synonyms: faricimab-svoa | RG-7716 | RG7716 | RO-6867461 | RO6867461 | Vabysmo®
Approved drug
faricimab is an approved drug (FDA (2022))
Compound class: Antibody
Comment: Faricimab is a bispecific monoclonal antibody that simultaneously binds to angiopoietin 2 (Ang2) and vascular endothelial growth factor A (VEGF-A) [3-4]. It is an angiogenesis inhibitor. The FcRn and FcγR binding sites of faricimab have been modified to disable its Fc‐mediated effector functions. Faricimab does not bind to Ang1 [4].
Classification Click here for help
Compound class Antibody
Approved drug? Yes (FDA (2022))
International Nonproprietary Names Click here for help
INN number INN
10563 faricimab
Synonyms Click here for help
faricimab-svoa | RG-7716 | RG7716 | RO-6867461 | RO6867461 | Vabysmo®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 793
Other databases
GtoPdb PubChem SID 440816789
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