faricimab   Click here for help

GtoPdb Ligand ID: 11420

Synonyms: RG-7716 | RG7716 | RO-6867461 | RO6867461
Compound class: Antibody
Comment: Faricimab is a clinical stage bispecific monoclonal antibody that binds to angiopoietin 2 (Ang2) and vascular endothelial growth factor A (VEGF-A) [3-4]. It is an angiogenesis inhibitor. The FcRn and FcγR binding sites of faricimab have been modified to disable its Fc‐mediated effector functions. Faricimab does not bind to ANG-1 [4].
Classification Click here for help
Compound class Antibody
International Nonproprietary Names Click here for help
INN number INN
10563 faricimab
Synonyms Click here for help
RG-7716 | RG7716 | RO-6867461 | RO6867461
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 793
Other databases
GtoPdb PubChem SID 440816789
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