VPC32183 [Ligand Id: 2908] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL184055 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| LPA1 receptor/Lysophosphatidic acid receptor Edg-2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3819] [GtoPdb: 272] [UniProtKB: Q92633] | ||||||||
| GtoPdb | - | - | 7.75 | pKi | - | - | - | Bioorg Med Chem Lett (2004) 14: 2735-40 [PMID:15125924] |
| ChEMBL | Inhibitory concentration against Lysophosphatidic acid 1 (LPA1) receptor | B | 6 | pIC50 | 992 | nM | IC50 | Bioorg Med Chem Lett (2004) 14: 4069-4074 [PMID:15225728] |
| LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793] | ||||||||
| GtoPdb | - | - | 6.96 | pIC50 | 109 | nM | IC50 | Bioorg Med Chem Lett (2004) 14: 2735-40 [PMID:15125924] |
| LPA3 receptor/Lysophosphatidic acid receptor Edg-7 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3250] [GtoPdb: 274] [UniProtKB: Q9UBY5] | ||||||||
| ChEMBL | Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor | B | 5.77 | pKi | 1688 | nM | Ki | Bioorg Med Chem Lett (2004) 14: 4069-4074 [PMID:15225728] |
| GtoPdb | - | - | 6.76 | pIC50 | 175 | nM | IC50 | Bioorg Med Chem Lett (2004) 14: 2735-40 [PMID:15125924] |
| GtoPdb | - | - | 6.76 | pIC50 | - | - | - | Bioorg Med Chem Lett (2004) 14: 2735-40 [PMID:15125924] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
