MB-28767 [Ligand Id: 1913] activity data from GtoPdb

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  • EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
  • EP1 receptor in Mouse [GtoPdb: 340] [UniProtKB: P35375]
  • EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597]
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  • EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
  • EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928]
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  • EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
  • EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
  • EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980]
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  • EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
  • EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240]
  • EP4 receptor in Rat [GtoPdb: 343] [UniProtKB: P43114]
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  • FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088]
  • FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117]
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  • TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995]
GtoPdb - - 6.4 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP1 receptor in Mouse [GtoPdb: 340] [UniProtKB: P35375]
GtoPdb - - 6.9 pKi - - - Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597]
GtoPdb - - 6.3 pKi - - - Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
GtoPdb - - 6 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944];
Mol Pharmacol (1999) 56: 545-51 [PMID:10462542]
EP2 receptor in Rat [GtoPdb: 341] [UniProtKB: Q62928]
GtoPdb - - 5.9 pKi - - - Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb - - 9.85 pKi 0.14 nM Ki Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Mouse [GtoPdb: 342] [UniProtKB: P30557]
GtoPdb - - 9.15 pKi 0.7 nM Ki Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980]
GtoPdb - - 9.26 pEC50 0.55 nM EC50 Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb - - 8 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944];
Mol Pharmacol (1999) 56: 545-51 [PMID:10462542]
GtoPdb - - 7.75 pEC50 17.7 nM EC50 J Pharmacol Exp Ther (2009) 331: 297-307 [PMID:19584306]
EP4 receptor in Mouse [GtoPdb: 343] [UniProtKB: P32240]
GtoPdb - - 6.3 pKi 500 nM Ki Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
EP4 receptor in Rat [GtoPdb: 343] [UniProtKB: P43114]
GtoPdb - - 7.6 pKi - - - Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820]
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088]
GtoPdb - - 6.3 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
FP receptor in Mouse [GtoPdb: 344] [UniProtKB: P43117]
GtoPdb - - 6.9 pKi - - - Br J Pharmacol (1997) 122: 217-24 [PMID:9313928]
TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731]
GtoPdb - - 6.5 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.