vantictumab [Ligand Id: 10197] activity data from GtoPdb

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  • FZD1 in Human [GtoPdb: 229] [UniProtKB: Q9UP38]
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  • FZD2 in Human [GtoPdb: 230] [UniProtKB: Q14332]
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  • FZD5 in Human [GtoPdb: 233] [UniProtKB: Q13467]
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  • FZD7 in Human [GtoPdb: 235] [UniProtKB: O75084]
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  • FZD8 in Human [GtoPdb: 236] [UniProtKB: Q9H461]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
FZD1 in Human [GtoPdb: 229] [UniProtKB: Q9UP38]
GtoPdb - - 9.15 pIC50 ~0.7 nM IC50 Proc Natl Acad Sci USA (2012) 109: 11717-22 [PMID:22753465]
FZD2 in Human [GtoPdb: 230] [UniProtKB: Q14332]
GtoPdb - - 8.96 pIC50 ~1.1 nM IC50 Proc Natl Acad Sci USA (2012) 109: 11717-22 [PMID:22753465]
FZD5 in Human [GtoPdb: 233] [UniProtKB: Q13467]
GtoPdb - - 8.96 pIC50 ~1.09 nM IC50 Proc Natl Acad Sci USA (2012) 109: 11717-22 [PMID:22753465]
FZD7 in Human [GtoPdb: 235] [UniProtKB: O75084]
GtoPdb - - 9 pIC50 ~1 nM IC50 Proc Natl Acad Sci USA (2012) 109: 11717-22 [PMID:22753465]
FZD8 in Human [GtoPdb: 236] [UniProtKB: Q9H461]
GtoPdb - - 8 pIC50 ~10 nM IC50 Proc Natl Acad Sci USA (2012) 109: 11717-22 [PMID:22753465]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.