GtoPdb Ligand ID: 9598

Synonyms: Hu23F2G | LeukArrest
Compound class: Antibody
Comment: Rovelizumab (Hu23F2G) is a humanized IgG4 bispecific monoclonal antibody targeting integrin alpha L subunit (ITGAL, CD11A) and integrin beta 2 subunit (ITGB2, CD18) [5], which are components of the leukocyte adhesion integrin LFA-1. Rovelizumab was developed by Icos Corporation (later acquired by Eli Lilly) for potential use in multiple sclerosis, myocardial infarction and ischemic stroke.
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.
Compound class Antibody
International Nonproprietary Names
INN number INN
7869 rovelizumab
Hu23F2G | LeukArrest
Database Links
Specialist databases
IMGT/mAb-DB 304
Other databases
GtoPdb PubChem SID 340590228
Search PubMed clinical trials rovelizumab
Search PubMed titles rovelizumab
Search PubMed titles/abstracts rovelizumab