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ChEMBL ligand: CHEMBL5095043 (Atamparib, Rbn 2397, Rbn-2397, RBN-2397, RBN2397) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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TCDD inducible poly(ADP-ribose) polymerase in Human [GtoPdb: 3266] [UniProtKB: Q7Z3E1] | ||||||||
GtoPdb | Binding affinity | - | 9.66 | pKd | 0.22 | nM | Kd | J Med Chem (2022) 65: 7532-7560 [PMID:35608571] |
GtoPdb | - | - | 8.52 | pIC50 | 3 | nM | IC50 | Eur J Med Chem (2022) 237: 114362 [PMID:35500474] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]