compound 10b [PMID: 26222319] [Ligand Id: 8731] activity data from GtoPdb

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  • poly(ADP-ribose) polymerase 1 in Human [GtoPdb: 2771] [UniProtKB: P09874]
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  • poly(ADP-ribose) polymerase 2 in Human [GtoPdb: 2772] [UniProtKB: Q9UGN5]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
poly(ADP-ribose) polymerase 1 in Human [GtoPdb: 2771] [UniProtKB: P09874]
GtoPdb - - 7.06 pKd 87 nM Kd J Med Chem (2015) 58: 6875-98 [PMID:26222319]
poly(ADP-ribose) polymerase 2 in Human [GtoPdb: 2772] [UniProtKB: Q9UGN5]
GtoPdb - - 6.9 pKd 125 nM Kd J Med Chem (2015) 58: 6875-98 [PMID:26222319]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.