flumbatinib [Ligand Id: 9913] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3545413 (Flumatinib, Flumbatinib, Hhgv-678, HH-GV678) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| platelet derived growth factor receptor beta in Human [GtoPdb: 1804] [UniProtKB: P09619] | ||||||||
| GtoPdb | - | - | 6.51 | pIC50 | 307 | nM | IC50 | Leukemia (2010) 24: 1807-9 [PMID:20703259] |
| KIT proto-oncogene, receptor tyrosine kinase in Human [GtoPdb: 1805] [UniProtKB: P10721] | ||||||||
| GtoPdb | - | - | 6.18 | pIC50 | 666 | nM | IC50 | Leukemia (2010) 24: 1807-9 [PMID:20703259] |
| ABL proto-oncogene 1, non-receptor tyrosine kinase in Human [GtoPdb: 1923] [UniProtKB: P00519] | ||||||||
| GtoPdb | - | - | 8.92 | pIC50 | 1.2 | nM | IC50 | Leukemia (2010) 24: 1807-9 [PMID:20703259] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
