bunolol [Ligand Id: 570] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL293030 (Bunolol) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588] | ||||||||
| GtoPdb | - | - | 8.4 | pKi | - | - | - | National Toxicology Program: Dept of Health and Human Services.. DrugMatrix |
| GtoPdb | - | - | 8.4 | pKi | 3.99 | nM | Ki | National Toxicology Program: Dept of Health and Human Services.. DrugMatrix |
| β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550] | ||||||||
| GtoPdb | - | - | 9.26 | pKi | 0.55 | nM | Ki | National Toxicology Program: Dept of Health and Human Services.. DrugMatrix |
| β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945] | ||||||||
| GtoPdb | - | - | 6.8 | pKi | 160 | nM | Ki | Eur J Pharmacol (2004) 484: 323-31 [PMID:14744619] |
| β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962] | ||||||||
| GtoPdb | - | - | 6.3 | pKi | - | - | - | Eur J Pharmacol (2004) 484: 323-31 [PMID:14744619] |
| β3-adrenoceptor in Rat [GtoPdb: 30] [UniProtKB: P26255] | ||||||||
| GtoPdb | - | - | 6.4 | pKi | - | - | - | Eur J Pharmacol (2004) 484: 323-31 [PMID:14744619] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
