levobunolol   Click here for help

GtoPdb Ligand ID: 570

Synonyms: (-)-bunolol | Ak-beta® | BRN 1887243 | L-bunolol | Liquifilm® | W-6421A
Approved drug
levobunolol is an approved drug (FDA (1985))
Compound class: Synthetic organic
Comment: Levobunolol is a nonselective β-adrenoceptor antagonist.
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: levobunolol

2D Structure
Click here for help
Click here for structure editor
Physico-chemical Properties
Click here for help
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 58.56
Molecular weight 291.18
XLogP 2.09
No. Lipinski's rules broken 0
Click here for help
Canonical SMILES OC(COc1cccc2c1CCCC2=O)CNC(C)(C)C
Isomeric SMILES O[C@H](COc1cccc2c1CCCC2=O)CNC(C)(C)C
InChI InChI=1S/C17H25NO3/c1-17(2,3)18-10-12(19)11-21-16-9-5-6-13-14(16)7-4-8-15(13)20/h5-6,9,12,18-19H,4,7-8,10-11H2,1-3H3/t12-/m0/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1985))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
4706 levobunolol
Synonyms Click here for help
(-)-bunolol | Ak-beta® | BRN 1887243 | L-bunolol | Liquifilm® | W-6421A
Database Links Click here for help
Specialist databases
GPCRdb Ligand levobunolol
Reactome Drug Reactome logo R-ALL-9610992
Reactome Reaction Reactome logo R-HSA-9609310
Other databases
CAS Registry No. 27591-01-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1201237
DrugBank Ligand DB01210
DrugCentral Ligand 431
GtoPdb PubChem SID 135650031
PubChem CID 39468
Search Google for chemical match using the InChIKey IXHBTMCLRNMKHZ-LBPRGKRZSA-N
Search Google for chemicals with the same backbone IXHBTMCLRNMKHZ
Search PubMed clinical trials levobunolol
Search PubMed titles levobunolol
Search PubMed titles/abstracts levobunolol
UniChem Compound Search for chemical match using the InChIKey IXHBTMCLRNMKHZ-LBPRGKRZSA-N
UniChem Connectivity Search for chemical match using the InChIKey IXHBTMCLRNMKHZ-LBPRGKRZSA-N
Wikipedia Levobunolol