flortaucipir (18F)   Click here for help

GtoPdb Ligand ID: 9100

Synonyms: 18F-AV-1451 | [F-18]T807 | flortaucipir F-18 | LY-3191748 | Tauvid®
 Ligand is labelled  Ligand is radioactive
Compound class: Synthetic organic
Comment: Flortaucipir (18F) is an investigational PET imaging agent (diagnostic radiopharmaceutical) designed to visualise tau protein (MAPT; P10636) in Alzheimer's disease brains. Compare with the approved agent, florbetapir, used to visualise β-amyloid.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 41.57
Molecular weight 263.09
XLogP 3.22
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
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Canonical SMILES Fc1ccc(cn1)c1ccc2c(c1)[nH]c1c2cncc1
Isomeric SMILES [18F]c1ccc(cn1)c1ccc2c(c1)[nH]c1c2cncc1
InChI InChI=1S/C16H10FN3/c17-16-4-2-11(8-19-16)10-1-3-12-13-9-18-6-5-14(13)20-15(12)7-10/h1-9,20H/i17-1
InChI Key GETAAWDSFUCLBS-SJPDSGJFSA-N
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
7-(6-fluoranylpyridin-3-yl)-5H-pyrido[4,3-b]indole
International Nonproprietary Names Click here for help
INN number INN
10203 flortaucipir (18F)
Synonyms Click here for help
18F-AV-1451 | [F-18]T807 | flortaucipir F-18 | LY-3191748 | Tauvid®
Database Links Click here for help
CAS Registry No. 1522051-90-6 (source: WHO INHN record)
ChEMBL Ligand CHEMBL3545253
GtoPdb PubChem SID 315661185
PubChem CID 70957463
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