flortaucipir (18F)   Click here for help

GtoPdb Ligand ID: 9100

Synonyms: 18F-AV-1451 | [F-18]T807 | flortaucipir F-18 | LY-3191748 | Tauvid®
 Ligand is labelled  Ligand is radioactive
Compound class: Synthetic organic
Comment: Flortaucipir (18F) is an investigational PET imaging agent (diagnostic radiopharmaceutical) designed to visualise tau protein (MAPT; P10636) in Alzheimer's disease brains. Compare with the approved agent, florbetapir, used to visualise β-amyloid.
2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 41.57
Molecular weight 263.09
XLogP 3.22
No. Lipinski's rules broken 0
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Canonical SMILES Fc1ccc(cn1)c1ccc2c(c1)[nH]c1c2cncc1
Isomeric SMILES [18F]c1ccc(cn1)c1ccc2c(c1)[nH]c1c2cncc1
InChI InChI=1S/C16H10FN3/c17-16-4-2-11(8-19-16)10-1-3-12-13-9-18-6-5-14(13)20-15(12)7-10/h1-9,20H/i17-1
Classification Click here for help
Compound class Synthetic organic
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
10203 flortaucipir (18F)
Synonyms Click here for help
18F-AV-1451 | [F-18]T807 | flortaucipir F-18 | LY-3191748 | Tauvid®
Database Links Click here for help
CAS Registry No. 1522051-90-6 (source: WHO INHN record)
ChEMBL Ligand CHEMBL3545253
DrugCentral Ligand 5396
GtoPdb PubChem SID 315661185
PubChem CID 70957463
Search Google for chemical match using the InChIKey GETAAWDSFUCLBS-SJPDSGJFSA-N
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UniChem Compound Search for chemical match using the InChIKey GETAAWDSFUCLBS-SJPDSGJFSA-N
UniChem Connectivity Search for chemical match using the InChIKey GETAAWDSFUCLBS-SJPDSGJFSA-N