XD1 [Ligand Id: 7525] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL142588
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  • bromodomain containing 4 in Human [GtoPdb: 1945] [UniProtKB: O60885]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Tubulin beta-1 chain in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1915] [UniProtKB: Q9H4B7]
ChEMBL Inhibitory concentration against tubulin assembly B 5.54 pIC50 2900 nM IC50 Bioorg. Med. Chem. Lett. (2005) 15: 235-238 [PMID:15582446]
bromodomain containing 4 in Human [GtoPdb: 1945] [UniProtKB: O60885]
GtoPdb - - 4.34 pKd 46000 nM Kd Angew Chem Int Ed Engl (2013) 52: 14055-9 [PMID:24272870]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]