anakinra [Ligand Id: 6972] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201570 (Alta2530, Alta-2530, AMG-719, Anakinra, Antril, Interleukin-1 receptor antagonist anakinra, Kineret, Osp-101)
  • Interleukin-1 receptor, type I in Human [GtoPdb: 1905]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Interleukin-1 receptor, type I in Human [GtoPdb: 1905]
GtoPdb - - 7.82 pKd 15 nM Kd J Biol Chem (1991) 266: 20311-5 [PMID:1834644]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]