GnRH I   Click here for help

GtoPdb Ligand ID: 1162

Synonyms: GnRH | gonadoliberin | gonadotropin releasing hormone | LH-RH (LHRH)
Species: Human, Mouse, Rat
Click here for help
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: gnrh

2D Structure
Click here for help
Click here for structure editor
Click here for help
Canonical SMILES OCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NCC(=O)N)CC(C)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(NC(=O)C1CCC(=O)N1)Cc1[nH]cnc1
Isomeric SMILES OCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N1CCCC1C(=O)NCC(=O)N)CC(C)C)Cc1c[nH]c2c1cccc2)Cc1ccc(cc1)O)NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C(NC(=O)C1CCC(=O)N1)Cc1[nH]cnc1
InChI InChI=1S/C60H73N15O13/c1-32(2)20-47(60(88)75-19-7-12-49(75)59(87)65-28-50(61)78)73-55(83)44(22-34-25-63-40-10-5-3-8-38(34)40)69-52(80)29-66-53(81)43(21-33-13-15-37(77)16-14-33)70-58(86)48(30-76)74-56(84)45(23-35-26-64-41-11-6-4-9-39(35)41)71-57(85)46(24-36-27-62-31-67-36)72-54(82)42-17-18-51(79)68-42/h3-6,8-11,13-16,25-27,31-32,42-49,63-64,76-77H,7,12,17-24,28-30H2,1-2H3,(H2,61,78)(H,62,67)(H,65,87)(H,66,81)(H,68,79)(H,69,80)(H,70,86)(H,71,85)(H,72,82)(H,73,83)(H,74,84)
Classification Click here for help
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Synonyms Click here for help
GnRH | gonadoliberin | gonadotropin releasing hormone | LH-RH (LHRH)
Gene/Precursor Click here for help
Gene symbol Gene name Species Precursor protein name Synonyms
GNRH1 gonadotropin releasing hormone 1 Human pro-GnRH 1 GNRH, gonadotropin-releasing hormone 1 (leutinizing-releasing hormone), gonadotropin-releasing hormone 1 (luteinizing-releasing hormone), GRH, LHRH
Gnrh1 gonadotropin releasing hormone 1 Mouse pro-GnRH 1 LHRH, LNRH
Gnrh1 gonadotropin releasing hormone 1 Rat pro-GnRH 1 Gnrh, GNRHA, Gonadotropin releasing hormone, gonadotropin releasing hormone 1, gonadotropin-releasing hormone 1, gonadotropin-releasing hormone 1 (luteinizing-releasing hormone), Lhrh, luteinizing hormone-releasing hormone, progonadoliberin-1, progonadoliberin I, RGNRHG1
Database Links Click here for help
Specialist databases
GPCRdb Ligand GnRH I
Other databases
Ensembl Gene ENSG00000147437 (Hs)
GtoPdb PubChem SID 135651779
Human Protein Atlas ENSG00000147437 (Hs)
PubChem CID 16132914
Search Google for chemical match using the InChIKey NMJREATYWWNIKX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone NMJREATYWWNIKX
UniChem Compound Search for chemical match using the InChIKey NMJREATYWWNIKX-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey NMJREATYWWNIKX-UHFFFAOYSA-N
UniProtKB P07490 (Rn), P13562 (Mm), P01148 (Hs)
Wikipedia Gonadotropin-releasing_hormone