GnRH I [Ligand Id: 1162] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| GnRH1 receptor in Human [GtoPdb: 256] [UniProtKB: P30968] | ||||||||
| GtoPdb | - | - | 8.54 | pKd | 2.9 | nM | Kd | Br J Pharmacol (2016) 173: 128-41 [PMID:26398856] |
| GtoPdb | - | - | 8.4 | pKi | 4 | nM | Ki | Br J Pharmacol (2016) 173: 128-41 [PMID:26398856] |
| GtoPdb | - | - | 8.4 | pKi | - | - | - |
Biochem Biophys Res Commun (2001) 289: 653-63 [PMID:11726197]; Endocrinology (2007) 148: 857-67 [PMID:17095587] |
| GtoPdb | - | - | 8.6 | pIC50 | - | - | - | J Biol Chem (2007) 282: 17921-9 [PMID:17452338] |
| GtoPdb | - | - | 10 | pEC50 | 0.1 | nM | EC50 | Biosens Bioelectron (2016) 79: 721-7 [PMID:26774084] |
| GnRH1 receptor in Mouse [GtoPdb: 256] [UniProtKB: Q01776] | ||||||||
| GtoPdb | - | - | 8.3 | pIC50 | - | - | - | J Biol Chem (1992) 267: 21281-4 [PMID:1328228] |
| GtoPdb | - | - | 7.92 | pEC50 | 12 | nM | EC50 | Biosens Bioelectron (2016) 79: 721-7 [PMID:26774084] |
| GnRH1 receptor in Rat [GtoPdb: 256] [UniProtKB: P30969] | ||||||||
| GtoPdb | - | - | 6.8 | pKi | - | - | - | Biochem Biophys Res Commun (2001) 289: 653-63 [PMID:11726197] |
| GtoPdb | - | - | 7.7 | pIC50 | - | - | - | Endocrinology (1994) 135: 315-20 [PMID:8013367] |
| GnRH2 receptor in Monkey [GtoPdb: 257] | ||||||||
| GtoPdb | - | - | 7.37 | pIC50 | 42.6 | nM | IC50 |
Endocr Rev (2004) 25: 235-75 [PMID:15082521]; Proc Natl Acad Sci USA (2001) 98: 9636-41 [PMID:11493674] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
