AM-6494 [Ligand Id: 10520] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| beta-secretase 1 in Human [GtoPdb: 2330] [UniProtKB: P56817] | ||||||||
| GtoPdb | - | - | 9.4 | pIC50 | 0.4 | nM | IC50 | J Med Chem (2020) 63: 2263-2281 [PMID:31589043] |
| beta-secretase 1 in Mouse [GtoPdb: 2330] [UniProtKB: P56818] | ||||||||
| GtoPdb | - | - | 9.44 | pIC50 | 0.36 | nM | IC50 | J Med Chem (2020) 63: 2263-2281 [PMID:31589043] |
| beta-secretase 1 in Rat [GtoPdb: 2330] [UniProtKB: P56819] | ||||||||
| GtoPdb | - | - | 9.21 | pIC50 | 0.62 | nM | IC50 | J Med Chem (2020) 63: 2263-2281 [PMID:31589043] |
| beta-secretase 2 in Human [GtoPdb: 2331] [UniProtKB: Q9Y5Z0] | ||||||||
| GtoPdb | - | - | 7.73 | pIC50 | 18.6 | nM | IC50 | J Med Chem (2020) 63: 2263-2281 [PMID:31589043] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
