peginterferon alfa-2b   

GtoPdb Ligand ID: 7462

Synonyms: PegIntron® | Sylatron®
peginterferon alfa-2b is an approved drug (EMA (2000), FDA (2001))
Comment: Peginterferon alfa-2b is a pegylated interferon protein. Conjugation with polyethylene glycol (PEG) is a strategy commonly used to protect peptide drugs from in vivo proteolytic breakdown to increase their biological half-life and duration of action.
Peginterferon alfa-2b is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Compound class Peptide or derivative
Approved drug? Yes (EMA (2000), FDA (2001))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
International Nonproprietary Names
INN number INN
7909 peginterferon alfa-2b
PegIntron® | Sylatron®
Database Links
Specialist databases
IMGT/mAb-DB 627
Other databases
ChEMBL Ligand CHEMBL1201561
DrugBank Ligand DB00022
GtoPdb PubChem SID 187051765
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Wikipedia Peginterferon alfa-2b