peginterferon alfa-2b   Click here for help

GtoPdb Ligand ID: 7462

Synonyms: PegIntron® | Sylatron®
Approved drug Immunopharmacology Ligand
peginterferon alfa-2b is an approved drug (EMA (2000), FDA (2001))
Comment: Peginterferon alfa-2b is a pegylated interferon protein. Conjugation with polyethylene glycol (PEG) is a strategy commonly used to protect peptide drugs from in vivo proteolytic breakdown to increase their biological half-life and duration of action.
Peginterferon alfa-2b is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Classification Click here for help
Compound class Peptide or derivative
Approved drug? Yes (EMA (2000), FDA (2001))
WHO Essential Medicine WHO Essential Medicines List (EML) (23rd List, 2023). Access PDF version.
Click to view more information about the WHO Model Lists of Essential Medicines.
International Nonproprietary Names Click here for help
INN number INN
7909 peginterferon alfa-2b
Synonyms Click here for help
PegIntron® | Sylatron®
Database Links Click here for help
Specialist databases
IMGT/mAb-DB 627
Other databases
ChEMBL Ligand CHEMBL1201561
DrugBank Ligand DB00022
GtoPdb PubChem SID 187051765
Search PubMed clinical trials peginterferon alfa-2b
Search PubMed titles peginterferon alfa-2b
Search PubMed titles/abstracts peginterferon alfa-2b
Wikipedia Peginterferon alfa-2b