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ChEMBL ligand: CHEMBL2104194 (Camleed, Enprostil, Gardrin, RS-84135) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] | ||||||||
GtoPdb | - | - | 7.8 | pKi | - | - | - |
Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]; J Pharm Pharmacol (2002) 54: 539-47 [PMID:11999132] |
EP1 receptor in Rat [GtoPdb: 340] [UniProtKB: P70597] | ||||||||
GtoPdb | - | - | 6.7 | pKi | - | - | - | Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820] |
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115] | ||||||||
GtoPdb | - | - | 7.92 | pKi | 12 | nM | Ki | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
GtoPdb | - | - | 8.43 | pEC50 | 3.7 | nM | EC50 | J Pharmacol Exp Ther (1998) 286: 1094-102 [PMID:9694973] |
EP3 receptor in Rat [GtoPdb: 342] [UniProtKB: P34980] | ||||||||
GtoPdb | - | - | 7.13 | pKi | 74 | nM | Ki | Eur J Pharmacol (1997) 340: 227-41 [PMID:9537820] |
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] | ||||||||
GtoPdb | - | - | 7.4 | pKi | - | - | - | Br J Pharmacol (2000) 130: 1919-1926 [PMID:10952683] |
FP receptor in Human [GtoPdb: 344] [UniProtKB: P43088] | ||||||||
GtoPdb | - | - | 7.1 | pKi | - | - | - | Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]