ChEMBL ligand: CHEMBL1082821
Cell division control protein 42 homolog in Human [ChEMBL: CHEMBL6088] [UniProtKB: P60953] There should be some charts here, you may need to enable JavaScript!
Protein kinase G (PKG) 2/cGMP-dependent protein kinase 2 in Human [ChEMBL: CHEMBL2896] [GtoPdb: 1493] [UniProtKB: Q13237] There should be some charts here, you may need to enable JavaScript!
protein kinase C epsilon/Protein kinase C epsilon in Human [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156] There should be some charts here, you may need to enable JavaScript!
protein kinase N2/Protein kinase N2 in Human [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513] There should be some charts here, you may need to enable JavaScript!
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Cell division control protein 42 homolog in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL6088] [UniProtKB: P60953]
ChEMBL	Inhibition of CDC42	B	7.27	pIC50	54	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-3749 [PMID:20471253]
Protein kinase G (PKG) 2/cGMP-dependent protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2896] [GtoPdb: 1493] [UniProtKB: Q13237]
ChEMBL	Inhibition of PRKG2	B	7.62	pIC50	24	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-3749 [PMID:20471253]
GtoPdb	-	-	7.62	pIC50	24	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-9 [PMID:20471253]
protein kinase C epsilon/Protein kinase C epsilon in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3582] [GtoPdb: 1486] [UniProtKB: Q02156]
ChEMBL	Inhibition of PRKCE	B	6	pIC50	1000	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-3749 [PMID:20471253]
protein kinase N2/Protein kinase N2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3032] [GtoPdb: 1521] [UniProtKB: Q16513]
GtoPdb	-	-	7.85	pIC50	14	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-9 [PMID:20471253]
ChEMBL	Inhibition of PRKCL2	B	7.85	pIC50	14	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-3749 [PMID:20471253]
Rho associated coiled-coil containing protein kinase 2/Rho-associated protein kinase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2973] [GtoPdb: 1504] [UniProtKB: O75116]
ChEMBL	Inhibition of ROCK2 by luciferase based ATP detection assay	B	8.4	pIC50	4	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-3749 [PMID:20471253]
GtoPdb	-	-	8.4	pIC50	4	nM	IC50	Bioorg Med Chem Lett (2010) 20: 3746-9 [PMID:20471253]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]