cefepime   Click here for help

GtoPdb Ligand ID: 10772

Synonyms: BMY-28142 | BMY28142 | CFPM | Maxipime® | Renapime®
Approved drug
cefepime is an approved drug (FDA (1996), UK (2017))
Compound class: Synthetic organic
Comment: Cefepime is a semisynthetic, broad-spectrum, fourth-generation cephalosporin antibacterial [1-2]. It was removed from the World Health Organization's List of Essential Medicines in 2019.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 8
Topological polar surface area 203.58
Molecular weight 480.12
XLogP -3.06
No. Lipinski's rules broken 0
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Canonical SMILES CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])C[N+]1(C)CCCC1
Isomeric SMILES CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])C[N+]1(C)CCCC1
InChI InChI=1S/C19H24N6O5S2/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29)/b23-12-/t13-,17-/m1/s1
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes (FDA (1996), UK (2017))
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
6092 cefepime
Synonyms Click here for help
BMY-28142 | BMY28142 | CFPM | Maxipime® | Renapime®
Database Links Click here for help
Specialist databases
Antibiotic DB Antibiotic DB Database logo Cefepime/VNRX-5133 | Cefepime | Cefepime/Enmetazobactam, AAI101, OCID 5090
Other databases
BindingDB Ligand 50350470
CAS Registry No. 88040-23-7 (source: WHO INN record)
DrugCentral Ligand 535
GtoPdb PubChem SID 405560213
PubChem CID 5479537
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UniChem Compound Search for chemical match using the InChIKey HVFLCNVBZFFHBT-ZKDACBOMSA-N
UniChem Connectivity Search for chemical match using the InChIKey HVFLCNVBZFFHBT-ZKDACBOMSA-N