cephalexin [Ligand Id: 4832] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1727 (Alsporin, Anhydrous cephalexin, Carnosporin, Cefadros, Cefaleksin, Cefalexin, Cefalexin anhydrous, Cephamasten, Durantel, Efalexin, Felexin, Garasin, Iwalexin, Keflet, Keflex, Kefloridina, Keftab, Lilly-66873, Mamalexin, NSC-758162, Oracocin, Pyassan, S-6437, Sinthecillin, Taicelexin, Uphalexin)
  • Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424]
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  • Peptide transporter 2/Solute carrier family 15 member 2 in Human [ChEMBL: CHEMBL1743125] [GtoPdb: 985] [UniProtKB: Q16348]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424]
ChEMBL TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells F 4.12 pKi 75000 nM Ki Eur J Pharm Biopharm (2005) 59: 17-24 [PMID:15567297]
ChEMBL TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells F 4.31 pKi 49000 nM Ki Am J Physiol (1997) 273: F706-F711 [PMID:9374833]
Peptide transporter 2/Solute carrier family 15 member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743125] [GtoPdb: 985] [UniProtKB: Q16348]
ChEMBL TP_TRANSPORTER: inhibition of Gly-Sar uptake in SKPT cells F 4.17 pKi 68200 nM Ki J Biol Chem (1995) 270: 25672-25677 [PMID:7592745]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]