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ChEMBL ligand: CHEMBL1727 (Keflet, Cefalexin, Cephalexin, 66873, Keftab, Keflex) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424] | ||||||||
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells | F | 4.12 | pKi | 75000 | nM | Ki | Eur. J. Pharm. Biopharm. (2005) 59: 17-24 [PMID:15567297] |
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells | F | 4.31 | pKi | 49000 | nM | Ki | Am. J. Physiol. (1997) 273: F706-F711 [PMID:9374833] |
Peptide transporter 2/Solute carrier family 15 member 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1743125] [GtoPdb: 985] [UniProtKB: Q16348] | ||||||||
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake in SKPT cells | F | 4.17 | pKi | 68200 | nM | Ki | J. Biol. Chem. (1995) 270: 25672-25677 [PMID:7592745] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]