propofol

Ligand id: 5464

Name: propofol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 20.23
Molecular weight 178.14
XLogP 4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1989))
WHO Essential Medicine WHO Model List of Essential Medicines (21st List, 2019). Access PDF version.
Prodrug fospropofol
IUPAC Name
2,6-bis(propan-2-yl)phenol
International Nonproprietary Names
INN number INN
5073 propofol
Synonyms
2,6-diisopropylphenol | Diprivan® | ICI 35868
Comments
Propofol is a short-acting (lasting 5-10 minutes) sedative.
Propofol is on the World Health Organisation's List of Essential Medicines. Click here to access the pdf version of the WHO's 21st Essential Medicines list (2019).
Database Links
CAS Registry No. 2078-54-8
ChEBI CHEBI:44915
ChEMBL Ligand CHEMBL526
DrugBank Ligand DB00818
GtoPdb PubChem SID 178102114
PubChem CID 4943
RCSB PDB Ligand PFL
Search Google for chemical match using the InChIKey OLBCVFGFOZPWHH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone OLBCVFGFOZPWHH
Search PubMed clinical trials propofol
Search PubMed titles propofol
Search PubMed titles/abstracts propofol
Search UniChem for chemical match using the InChIKey OLBCVFGFOZPWHH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone OLBCVFGFOZPWHH
Wikipedia Propofol