SCH 50911 [Ligand Id: 1075] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1895916
  • GABAB1 in Rat [GtoPdb: 240] [UniProtKB: Q9Z0U4]
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  • GABAB receptor in Human [GtoPdb: 242]
  • GABAB receptor in Rat [GtoPdb: 242]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GABAB1 in Rat [GtoPdb: 240] [UniProtKB: Q9Z0U4]
GtoPdb - - 6.4 pIC50 - - - J Pharmacol Exp Ther (1995) 274: 1393-8 [PMID:7562513]
GABAB receptor in Human [GtoPdb: 242]
GtoPdb - - 6 pKi - - - Br J Pharmacol (2000) 131: 1050-4 [PMID:11082110];
Biochem Pharmacol (2003) 65: 1103-13 [PMID:12663046]
GABAB receptor in Rat [GtoPdb: 242]
GtoPdb - - 6.5 pIC50 - - - J Pharmacol Exp Ther (1995) 274: 1393-8 [PMID:7562513]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]