SB590885 [Ligand Id: 9389] activity data from GtoPdb

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  • B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
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  • Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
GtoPdb In a cell-free assay - 9.8 pKi 0.16 nM Ki Cancer Res (2006) 66: 11100-5 [PMID:17145850]
Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049]
GtoPdb In a cell-free assay - 8.76 pIC50 1.72 nM IC50 Cancer Res (2006) 66: 11100-5 [PMID:17145850]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.