ChEMBL ligand: CHEMBL2218896 (Cesamet, CPD 109514, CPD-109514, Nabilona, Nabilone)
CB1 receptor/Cannabinoid receptor 1 in Human [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554] CB1 receptor/Cannabinoid receptor 1 in Rat [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272] There should be some charts here, you may need to enable JavaScript!
CB2 receptor/Cannabinoid receptor 2 in Human [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972] CB2 receptor/Cannabinoid receptor 2 in Mouse [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
CB1 receptor/Cannabinoid receptor 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL218] [GtoPdb: 56] [UniProtKB: P21554]
ChEMBL	Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cells	B	8.29	pKi	5.1	nM	Ki	Bioorg Med Chem Lett (2010) 20: 4992-4998 [PMID:20688519]
GtoPdb	-	-	8.4	pKi	3.98	nM	Ki	Eur J Med Chem (2011) 46: 5086-98 [PMID:21885167]
ChEMBL	Displacement of [3H]-CP55940 from human CB1 receptor expressed in CHO cells by liquid scintillation counting	B	8.4	pKi	3.98	nM	Ki	Eur J Med Chem (2011) 46: 5086-5098 [PMID:21885167]
ChEMBL	Binding affinity against human cannabinoid receptor by using radioligand ([3H]CP-55940) assay.	B	8.66	pKi	2.19	nM	Ki	Bioorg Med Chem Lett (1996) 6: 189-194
ChEMBL	Binding affinity to human CB1 receptor	B	8.66	pKi	2.19	nM	Ki	J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL	Agonist activity at human recombinant CB1 receptor expressed in CHO cells assessed as effect on CP-55940 induced PLA2 activation by [3H]arachidonic acid release assay	F	8.4	pEC50	3.98	nM	EC50	Bioorg Med Chem Lett (2010) 20: 4992-4998 [PMID:20688519]
ChEMBL	Agonist activity at human CB1 receptor expressed in CHO cells assessed as stimulation of [3H]-arachidonic acid release	F	8.4	pEC50	3.98	nM	EC50	Eur J Med Chem (2011) 46: 5086-5098 [PMID:21885167]
CB1 receptor/Cannabinoid receptor 1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3571] [GtoPdb: 56] [UniProtKB: P20272]
ChEMBL	Displacement of [3H]CP55940 from rat brain CB1 receptor	B	8.66	pKi	2.2	nM	Ki	J Med Chem (2010) 53: 6996-7010 [PMID:20925434]
CB2 receptor/Cannabinoid receptor 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL253] [GtoPdb: 57] [UniProtKB: P34972]
ChEMBL	Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cells	B	7.75	pKi	17.6	nM	Ki	Bioorg Med Chem Lett (2010) 20: 4992-4998 [PMID:20688519]
ChEMBL	Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cells by liquid scintillation counting	B	8.2	pKi	6.31	nM	Ki	Eur J Med Chem (2011) 46: 5086-5098 [PMID:21885167]
GtoPdb	-	-	8.2	pKi	6.31	nM	Ki	Eur J Med Chem (2011) 46: 5086-98 [PMID:21885167]
ChEMBL	Binding affinity against human Cannabinoid receptor 2 by using radioligand ([3H]CP-55940) assay.	B	8.74	pKi	1.84	nM	Ki	Bioorg Med Chem Lett (1996) 6: 189-194
ChEMBL	Binding affinity to human CB2 receptor	B	8.74	pKi	1.84	nM	Ki	J Med Chem (2013) 56: 8224-8256 [PMID:23865723]
ChEMBL	Agonist activity at human CB2 receptor expressed in CHO cells assessed as increase of forskolin-stimulated cAMP accumulation after 20 mins	F	7.8	pEC50	15.85	nM	EC50	Eur J Med Chem (2011) 46: 5086-5098 [PMID:21885167]
CB2 receptor/Cannabinoid receptor 2 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5373] [GtoPdb: 57] [UniProtKB: P47936]
ChEMBL	Displacement of [3H]CP55940 from mouse spleen CB2 receptor	B	8.74	pKi	1.8	nM	Ki	J Med Chem (2010) 53: 6996-7010 [PMID:20925434]

ChEMBL data shown on this page come from version 36:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]