forasartan   Click here for help

GtoPdb Ligand ID: 6896

Synonyms: SC-52458
Approved drug
forasartan is an approved drug
Compound class: Synthetic organic
Comment: Forasartan is a nonpeptide, competitive and reversible angiotensin II receptor antagonist, selective for the AT1 receptor. Forasartan is not a popular drug of choice for hypertension as it is less effective than losartan, due to its relatively short duration of action.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 98.06
Molecular weight 416.24
XLogP 6.25
No. Lipinski's rules broken 1
SMILES / InChI / InChIKey
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Canonical SMILES CCCCc1nc(nn1Cc1ccc(nc1)c1ccccc1c1n[nH]nn1)CCCC
Isomeric SMILES CCCCc1nc(nn1Cc1ccc(nc1)c1ccccc1c1n[nH]nn1)CCCC
InChI InChI=1S/C23H28N8/c1-3-5-11-21-25-22(12-6-4-2)31(28-21)16-17-13-14-20(24-15-17)18-9-7-8-10-19(18)23-26-29-30-27-23/h7-10,13-15H,3-6,11-12,16H2,1-2H3,(H,26,27,29,30)
InChI Key YONOBYIBNBCDSJ-UHFFFAOYSA-N
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
5-[(3,5-dibutyl-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine
International Nonproprietary Names Click here for help
INN number INN
7415 forasartan
Synonyms Click here for help
SC-52458
Database Links Click here for help
CAS Registry No. 145216-43-9 (source: Scifinder)
ChEMBL Ligand CHEMBL315021
DrugBank Ligand DB01342
GtoPdb PubChem SID 178103478
PubChem CID 132706
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Wikipedia Forasartan