forasartan   Click here for help

GtoPdb Ligand ID: 6896

Synonyms: SC-52458
Approved drug
forasartan is an approved drug
Compound class: Synthetic organic
Comment: Forasartan is a nonpeptide, competitive and reversible angiotensin II receptor antagonist, selective for the AT1 receptor. Forasartan is not a popular drug of choice for hypertension as it is less effective than losartan, due to its relatively short duration of action.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 10
Topological polar surface area 98.06
Molecular weight 416.24
XLogP 6.25
No. Lipinski's rules broken 1
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Canonical SMILES CCCCc1nc(nn1Cc1ccc(nc1)c1ccccc1c1n[nH]nn1)CCCC
Isomeric SMILES CCCCc1nc(nn1Cc1ccc(nc1)c1ccccc1c1n[nH]nn1)CCCC
InChI InChI=1S/C23H28N8/c1-3-5-11-21-25-22(12-6-4-2)31(28-21)16-17-13-14-20(24-15-17)18-9-7-8-10-19(18)23-26-29-30-27-23/h7-10,13-15H,3-6,11-12,16H2,1-2H3,(H,26,27,29,30)
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
7415 forasartan
Synonyms Click here for help
Database Links Click here for help
Specialist databases
GPCRdb Ligand forasartan
Reactome Drug Reactome logo R-ALL-9615735
Reactome Reaction Reactome logo R-HSA-9615249
Other databases
CAS Registry No. 145216-43-9 (source: Scifinder)
ChEMBL Ligand CHEMBL315021
DrugBank Ligand DB01342
GtoPdb PubChem SID 178103478
PubChem CID 132706
Search Google for chemical match using the InChIKey YONOBYIBNBCDSJ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YONOBYIBNBCDSJ
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UniChem Compound Search for chemical match using the InChIKey YONOBYIBNBCDSJ-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey YONOBYIBNBCDSJ-UHFFFAOYSA-N
Wikipedia Forasartan