α-cyanocinnamate [Ligand Id: 11299] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL77595
  • mitochondrial pyruvate carrier 1 in Rat [GtoPdb: 3022] [UniProtKB: P63031]
  • This target only has 0 pki data point
1 CHEMBL77595_lig_chart_1 mitochondrial pyruvate carrier 1 Rat
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  • mitochondrial pyruvate carrier 2 in Rat [GtoPdb: 3023] [UniProtKB: P38718]
  • This target only has 0 pki data point
2 CHEMBL77595_lig_chart_2 mitochondrial pyruvate carrier 2 Rat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mitochondrial pyruvate carrier 1 in Rat [GtoPdb: 3022] [UniProtKB: P63031]
GtoPdb - - 6.7 pIC50 200 nM IC50 Biochem J (1975) 148: 85-96 [PMID:1156402]
mitochondrial pyruvate carrier 2 in Rat [GtoPdb: 3023] [UniProtKB: P38718]
GtoPdb - - 6.7 pIC50 200 nM IC50 Biochem J (1975) 148: 85-96 [PMID:1156402]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]