mepyramine   

GtoPdb Ligand ID: 1227

Synonyms: Anthisan® | mepiramine | mepyramine maleate | pyrilamine | pyrilamine tannate | Pyrlex®
mepyramine is an approved drug
Compound class: Synthetic organic
Comment: Mepyramine (also commonly referred to as pyrilamine) is a first generation antihistamine. As it can cross the blood-brain barrier easily it causes substantial drowsiness.
IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: mepyramine

2D Structure
Click here for structure editor
Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 28.6
Molecular weight 285.18
XLogP 3.19
No. Lipinski's rules broken 0
SMILES / InChI / InChIKey
Canonical SMILES COc1ccc(cc1)CN(c1ccccn1)CCN(C)C
Isomeric SMILES COc1ccc(cc1)CN(c1ccccn1)CCN(C)C
InChI InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3
InChI Key YECBIJXISLIIDS-UHFFFAOYSA-N
Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine
International Nonproprietary Names
INN number INN
106 mepyramine
Synonyms
Anthisan® | mepiramine | mepyramine maleate | pyrilamine | pyrilamine tannate | Pyrlex®
Database Links
CAS Registry No. 91-84-9 (source: ChEBI)
ChEBI CHEBI:6762
ChEMBL Ligand CHEMBL511
DrugBank Ligand DB06691
DrugCentral Ligand 2331
GtoPdb PubChem SID 135650867
PubChem CID 4992
Search Google for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YECBIJXISLIIDS
Search PubMed clinical trials mepyramine
Search PubMed titles mepyramine
Search PubMed titles/abstracts mepyramine
Search UniChem for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone YECBIJXISLIIDS
Wikipedia Mepyramine