mepyramine   Click here for help

GtoPdb Ligand ID: 1227

Synonyms: Anthisan® | mepiramine | mepyramine maleate | pyrilamine | pyrilamine tannate | Pyrlex®
Approved drug Immunopharmacology Ligand
mepyramine is an approved drug
Compound class: Synthetic organic
Comment: Mepyramine (also commonly referred to as pyrilamine) is a first generation antihistamine. As it can cross the blood-brain barrier easily it causes substantial drowsiness.
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2D Structure
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Physico-chemical Properties
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Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 28.6
Molecular weight 285.18
XLogP 3.19
No. Lipinski's rules broken 0
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Canonical SMILES COc1ccc(cc1)CN(c1ccccn1)CCN(C)C
Isomeric SMILES COc1ccc(cc1)CN(c1ccccn1)CCN(C)C
InChI InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3
Classification Click here for help
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name Click here for help
International Nonproprietary Names Click here for help
INN number INN
106 mepyramine
Synonyms Click here for help
Anthisan® | mepiramine | mepyramine maleate | pyrilamine | pyrilamine tannate | Pyrlex®
Database Links Click here for help
Specialist databases
GPCRdb Ligand mepyramine
Other databases
CAS Registry No. 91-84-9 (source: ChEBI)
DrugBank Ligand DB06691
DrugCentral Ligand 2331
GtoPdb PubChem SID 135650867
PubChem CID 4992
Search Google for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
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UniChem Compound Search for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
UniChem Connectivity Search for chemical match using the InChIKey YECBIJXISLIIDS-UHFFFAOYSA-N
Wikipedia Mepyramine