Ligand id: 1227

Name: mepyramine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 28.6
Molecular weight 285.18
XLogP 3.19
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Immunopharmacology Comments
Mepyramine is a histamine H1 receptor antagonist that blocks the action of endogenous histamine to mediate its anti-inflammatory effect.
Immunopharmacology Disease
Disease X-Refs Comment References
Allergic urticaria Disease Ontology: DOID:10612
Mepyramine is a topically applied antihistamine that can be used to treat allergic urticaria and the inflammation associated with bites and stings.