nirmatrelvir [Ligand Id: 11503] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111] | ||||||||
| GtoPdb | Determined in vitro, in a TR-FRET enzyme assay | - | 9.57 | pKi | 0.27 | nM | Ki | Science (2021) 374: 1586-1593 [PMID:34726479] |
| GtoPdb | - | - | 7.48 | pIC50 | 33 | nM | IC50 | J Am Chem Soc (2022) 144: 2905-2920 [PMID:35142215] |
| GtoPdb | - | - | 7.72 | pIC50 | 19 | nM | IC50 | |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
