compound 9 [PMID: 1738140] [Ligand Id: 8677] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL309130
  • Arginyl aminopeptidase/Aminopeptidase B in Human [ChEMBL: CHEMBL2432] [GtoPdb: 1564] [UniProtKB: Q9H4A4]
  • Arginyl aminopeptidase/Aminopeptidase B in Rat [ChEMBL: CHEMBL2452] [GtoPdb: 1564] [UniProtKB: O09175]
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  • Aminopeptidase A/Aspartyl aminopeptidase in Human [ChEMBL: CHEMBL2761] [GtoPdb: 1559] [UniProtKB: Q9ULA0]
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  • Leucine aminopeptidase 3/Leucine aminopeptidase in Human [ChEMBL: CHEMBL3965] [GtoPdb: 1569] [UniProtKB: P28838]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Arginyl aminopeptidase/Aminopeptidase B in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2432] [GtoPdb: 1564] [UniProtKB: Q9H4A4]
ChEMBL Compound was tested for binding affinity towards arginyl aminopeptidase B 4.41 pKi 39000 nM Ki J. Med. Chem. (1992) 35: 451-456 [PMID:1738140]
Arginyl aminopeptidase/Aminopeptidase B in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2452] [GtoPdb: 1564] [UniProtKB: O09175]
ChEMBL Inhibitory activity against aminopeptidase B B 4.41 pKi 39000 nM Ki J. Med. Chem. (1988) 31: 2193-2199 [PMID:3184126]
Aminopeptidase N in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1907] [GtoPdb: 1560] [UniProtKB: P15144]
ChEMBL Compound was tested for binding affinity towards microsomal aminopeptidase B 4.7 pKi 20000 nM Ki J. Med. Chem. (1992) 35: 451-456 [PMID:1738140]
Aminopeptidase N in Pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2590] [UniProtKB: P15145]
ChEMBL Inhibitory activity against Aminopeptidase M B 4.7 pKi 20000 nM Ki J. Med. Chem. (1988) 31: 2193-2199 [PMID:3184126]
Aminopeptidase A/Aspartyl aminopeptidase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2761] [GtoPdb: 1559] [UniProtKB: Q9ULA0]
GtoPdb - - 6.29 pKi 510 nM Ki J Med Chem (1992) 35: 451-6 [PMID:1738140]
ChEMBL Compound was tested for binding affinity towards cytosolic aminopeptidase B 6.29 pKi 510 nM Ki J. Med. Chem. (1992) 35: 451-456 [PMID:1738140]
Leucine aminopeptidase 3/Leucine aminopeptidase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3965] [GtoPdb: 1569] [UniProtKB: P28838]
ChEMBL Inhibitory activity against Leucine aminopeptidase B 6.29 pKi 510 nM Ki J. Med. Chem. (1988) 31: 2193-2199 [PMID:3184126]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]