Arginyl aminopeptidase | M1: Aminopeptidase N | IUPHAR/BPS Guide to PHARMACOLOGY

Top ▲

Arginyl aminopeptidase

Target not currently curated in GtoImmuPdb

Target id: 1564

Nomenclature: Arginyl aminopeptidase

Family: M1: Aminopeptidase N

Annotation status:  image of a grey circle Awaiting annotation/under development. Please contact us if you can help with annotation.  » Email us

Gene and Protein Information
Species TM AA Chromosomal Location Gene Symbol Gene Name Reference
Human - 650 1q32 RNPEP arginyl aminopeptidase
Mouse - 650 1 E4 Rnpep arginyl aminopeptidase (aminopeptidase B)
Rat - 648 13q13 Rnpep arginyl aminopeptidase
Previous and Unofficial Names
AP-B | arginine aminopeptidase | cytosol aminopeptidase IV | arginyl aminopeptidase (aminopeptidase B)
Database Links
Specialist databases
MEROPS M01.014 (Hs)
Other databases
ChEMBL Target
Ensembl Gene
Entrez Gene
Human Protein Atlas
KEGG Enzyme
RefSeq Nucleotide
RefSeq Protein
Enzyme Reaction
EC Number:

Download all structure-activity data for this target as a CSV file

Key to terms and symbols View all chemical structures Click column headers to sort
Ligand Sp. Action Value Parameter Reference
Lys-thiol N/A Inhibition 9.1 pKi 1
pKi 9.1 (Ki 9x10-10 M) [1]


Show »

1. Ocain TD, Rich DH. (1987) L-lysinethiol: a subnanomolar inhibitor of aminopeptidase B. Biochem. Biophys. Res. Commun., 145 (3): 1038-42. [PMID:3111463]

How to cite this page

M1: Aminopeptidase N: Arginyl aminopeptidase. Last modified on 28/07/2015. Accessed on 04/04/2020. IUPHAR/BPS Guide to PHARMACOLOGY,