ChEMBL ligand: CHEMBL13817 (Ibutamoren, L-163,191, MK-677)
ghrelin receptor/Ghrelin receptor in Human [ChEMBL: CHEMBL4616] [GtoPdb: 246] [UniProtKB: Q92847] ghrelin receptor/Ghrelin receptor in Rat [ChEMBL: CHEMBL3278] [GtoPdb: 246] [UniProtKB: O08725] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
ghrelin receptor/Ghrelin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4616] [GtoPdb: 246] [UniProtKB: Q92847]
ChEMBL	Compound was evaluated for binding affinity using [35S]MK-0677 (800-1100 Ci/mmol), as radioligand having specific high activity	B	9.85	pKd	0.14	nM	Kd	J Med Chem (1998) 41: 3103-3127 [PMID:9703459]
GtoPdb	-	-	9.34	pKi	0.46	nM	Ki	Eur J Endocrinol (1999) 141: 180-9 [PMID:10427162]
ChEMBL	Binding Affinity against Growth hormone secretagogue receptor of swine using [35S]MK-0677 as radioligand	B	9.62	pKi	0.24	nM	Ki	J Med Chem (1996) 39: 1767-1770 [PMID:8627599]
ChEMBL	Binding affinity for human growth hormone GH secretagogue (hGHsr) receptor	B	6.52	pIC50	300	nM	IC50	Bioorg Med Chem Lett (2000) 10: 5-8 [PMID:10636230]
ChEMBL	Binding affinity towards human pituitary Growth hormone secretagogue receptor using [125I][Tyr4]-ghrelin as radioligand	B	7.49	pIC50	32	nM	IC50	J Med Chem (2003) 46: 1191-1203 [PMID:12646029]
ChEMBL	Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay	B	8.7	pIC50	2	nM	IC50	J Med Chem (2018) 61: 5974-5987 [PMID:29909635]
ChEMBL	Displacement of human [125I]-ghrelin from GHS-R1a (unknown origin) expressed in HEK293 cell membranes after 1 hr by radioligand binding assay	B	8.7	pIC50	2	nM	IC50	J Med Chem (2018) 61: 5974-5987 [PMID:29909635]
ChEMBL	Binding affinity towards cloned human Growth hormone secretagogue receptor type I in LLC PK-1 cells using [125I][His9]-ghrelin as radioligand	B	9.12	pIC50	0.76	nM	IC50	J Med Chem (2003) 46: 1191-1203 [PMID:12646029]
ChEMBL	Binding affinity towards human Growth hormone secretagogue receptor type 1 using competitive binding assay with radiolabeled [35S]-MK-0677 expressed as IC50	B	9.2	pIC50	0.63	nM	IC50	Bioorg Med Chem Lett (2001) 11: 1955-1957 [PMID:11459669]
ChEMBL	Ability to displace [125I]ghrelin from cloned human Growth hormone secretagogue receptor type I (GSH1a) receptor expressed in COS-7 cells	B	9.29	pIC50	0.51	nM	IC50	J Med Chem (2002) 45: 5609-5616 [PMID:12477342]
ChEMBL	Inhibition against human growth hormone secretagogue (GHS) receptor	B	9.4	pIC50	0.4	nM	IC50	J Med Chem (2004) 47: 888-899 [PMID:14761190]
ChEMBL	Functional potency measured as intracellular calcium elevation in Hek-293 cells expressing hGHSR1a	F	8.84	pEC50	1.43	nM	EC50	Bioorg Med Chem Lett (2001) 11: 1955-1957 [PMID:11459669]
ChEMBL	Agonist activity at human GHS-R1	F	8.87	pEC50	1.35	nM	EC50	Bioorg Med Chem (2007) 15: 3054-3064 [PMID:17329109]
ChEMBL	Agonist activity at human GHS-R1	F	8.89	pEC50	1.3	nM	EC50	Bioorg Med Chem (2007) 15: 3054-3064 [PMID:17329109]
ChEMBL	Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysis	F	9.4	pEC50	0.4	nM	EC50	J Med Chem (2018) 61: 5974-5987 [PMID:29909635]
ChEMBL	Agonist activity at human GHS receptor assessed as intracellular myo-IP1 secretion after 90 mins by HTRF analysis	F	9.4	pEC50	0.4	nM	EC50	J Med Chem (2018) 61: 5974-5987 [PMID:29909635]
ChEMBL	Agonist activity at GHSR (unknown origin)	B	9.7	pEC50	0.2	nM	EC50	J Med Chem (2013) 56: 1197-1210 [PMID:23281966]
GtoPdb	-	-	9.72	pEC50	0.19	nM	EC50	Mol Endocrinol (2005) 19: 2400-11 [PMID:15905359]; Eur J Endocrinol (1999) 141: 180-9 [PMID:10427162]
ghrelin receptor/Ghrelin receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3278] [GtoPdb: 246] [UniProtKB: O08725]
ChEMBL	In vitro growth hormone release was determined in rat pituitary cell assay	F	8.89	pEC50	1.3	nM	EC50	Bioorg Med Chem Lett (1998) 8: 107-112 [PMID:9925440]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]