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Synonyms: XC-302 | XC302
Compound class: Synthetic organic
Comment: Puquitinib is an orally active, PI3 kinase inhibitor that induces autophagy by inhibiting the PI3K/AKT/mTOR signaling pathway. Puquitinib is selective for p110δ relative to other PI3K class I enzymes. It is a clinical lead developed for antitumour activity .
Puquitinib is a 'pseudo' INN, that takes the form of an INN, but has not been submitted to the World Health Organisation for ratification.
Ligand Activity Visualisation Charts
These are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts.✖
|Compound class||Synthetic organic|
|XC-302 | XC302|
|GtoPdb PubChem SID||363894222|
|Search Google for chemical match using the InChIKey||QUTFBURLXCODBH-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||QUTFBURLXCODBH|
|UniChem Compound Search for chemical match using the InChIKey||QUTFBURLXCODBH-UHFFFAOYSA-N|
|UniChem Connectivity Search for chemical match using the InChIKey||QUTFBURLXCODBH-UHFFFAOYSA-N|