lifirafenib [Ligand Id: 8958] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Inhibition of wild type EGFR kinase domain (aa669-1210) | - | 7.54 | pIC50 | 29 | nM | IC50 | Mol Cancer Ther (2015) 14: 2187-97 [PMID:26208524] |
| A-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1933] [UniProtKB: P10398] | ||||||||
| GtoPdb | - | - | 8.25 | pIC50 | 5.6 | nM | IC50 | Mol Cancer Ther (2015) 14: 2187-97 [PMID:26208524] |
| B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056] | ||||||||
| GtoPdb | Inhibition of wild type BRAF kinase domain (aa416-766) | - | 7.49 | pIC50 | 32 | nM | IC50 | Mol Cancer Ther (2015) 14: 2187-97 [PMID:26208524] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
